The Solubility–Permeability Interplay: Mechanistic Modeling and Predictive Application of the Impact of Micellar Solubilization on Intestinal Permeation-Reference-Cited by-同舟云学术

The Solubility–Permeability Interplay: Mechanistic Modeling and Predictive Application of the Impact of Micellar Solubilization on Intestinal Permeation

Published:2011-08-11 Issue:5 Volume:8 Page:1848-1856
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Miller Jonathan M.¹,Beig Avital²,Krieg Brian J.³,Carr Robert A.¹,Borchardt Thomas B.¹,Amidon Gregory E.³,Amidon Gordon L.³,Dahan Arik²

Affiliation:

1. Global Pharmaceutical Research and Development, Abbott Laboratories, Abbott Park, Illinois 60064, United States

2. Department of Clinical Pharmacology, School of Pharmacy, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel

3. Department of Pharmaceutical Sciences, The University of Michigan College of Pharmacy, 428 Church Street, Ann Arbor Michigan 48109, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/mp200181v

Reference36 articles.

1. Drug-like properties and the causes of poor solubility and poor permeability

2. Property-Based Design: Optimization of Drug Absorption and Pharmacokinetics

3. Modern bioavailability, bioequivalence and biopharmaceutics classification system. New scientific approaches to international regulatory standards

4. A Mechanistic Approach to Understanding the Factors Affecting Drug Absorption: A Review of Fundamentals

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