Synthesis and Structure–Activity Relationships of Indazole Arylsulfonamides as Allosteric CC-Chemokine Receptor 4 (CCR4) Antagonists

Author:

Procopiou Panayiotis A.,Barrett John W.,Barton Nicholas P.1,Begg Malcolm,Clapham David2,Copley Royston C. B.1,Ford Alison J.,Graves Rebecca H.,Hall David A.,Hancock Ashley P.,Hill Alan P.1,Hobbs Heather,Hodgson Simon T.,Jumeaux Coline,Lacroix Yannick M. L.,Miah Afjal H.,Morriss Karen M. L.,Needham Deborah,Sheriff Emma B.,Slack Robert J.,Smith Claire E.,Sollis Steven L.,Staton Hugo

Affiliation:

1. Computational and Structural Chemistry Department, Platform Technology & Science, GlaxoSmithKline Medicines Research Centre, Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, United Kingdom

2. Exploratory Development Sciences, Platform Technology & Science, Research & Development, GlaxoSmithKline, Park Road, Ware, Hertfordshire SG12 ODP, United Kingdom

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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