Diminished Reactivity of Ortho-Substituted Phenacyl Bromides toward Nucleophilic Displacement-Reference-Cited by-同舟云学术

Diminished Reactivity of Ortho-Substituted Phenacyl Bromides toward Nucleophilic Displacement

Published:2003-01-23 Issue:4 Volume:68 Page:1594-1596
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Kalendra Diane M.¹,Sickles Barry R.¹

Affiliation:

1. Chemical Development Department, GlaxoSmithKline Co., 5 Moore Drive, Research Triangle Park, North Carolina 27709 barry.r.sickles@gsk.com

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jo011042o

Reference11 articles.

1. Stereochemical and Steric Effects in Nucleophilic Substitution of α-Halo Ketones

2. The Effect of the Carbonyl and Related Groups on the Reactivity of Halides in SN2 Reactions

3. Synthesis and evaluation of the anticonvulsant activity of a series of 2-amino-1-phenyl-1-propanols derived from the metabolites of the antidepressant bupropion

4. Dewar, M. J. S.The Electronic Theory of Organic Chemistry; Oxford University Press: London, England, 1949; p 73. And later: Carey, F. A.; Sundberg, R. J.Advanced Organic Chemistry, 3rd ed.; Plenum Press: New York, 1990; Part A, p 296.

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