Synthesis and Biological Activity of Phosphonate Analogues and Geometric Isomers of the Highly Potent Phosphoantigen (E)-1-Hydroxy-2-methylbut-2-enyl 4-Diphosphate-Reference-Cited by-同舟云学术

Synthesis and Biological Activity of Phosphonate Analogues and Geometric Isomers of the Highly Potent Phosphoantigen (E)-1-Hydroxy-2-methylbut-2-enyl 4-Diphosphate

Published:2008-02-28 Issue:6 Volume:51 Page:1747-1754
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Boëdec Angélique¹,Sicard Hélène¹,Dessolin Jean¹,Herbette Gaëtan¹,Ingoure Sophie¹,Raymond Cédric¹,Belmant Christian¹,Kraus Jean-Louis¹

Affiliation:

1. Innate Pharma, 121 Ancien Chemin de Cassis, 13009 Marseille, France, UMR 5248 CBMN, CNRS-Université Bordeaux 1-ENITAB, Institut Européen de Chimie et Biologie (IECB), 2 rue Robert Escarpit, 33607 Pessac Cedex, France, Spectropole, Université Paul Cézanne, Avenue Escadrille Normandie Niémen, 13397 Marseille Cedex 20, France, and Laboratoire de Chimie Biomoléculaire, IBDML, UMR 6216, CNRS, Université de la Méditerranée, Parc scientifique de Luminy, 13288 Marseille cedex 09, France

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm701101g

Reference23 articles.

1. Stimulation of Human γδ T Cells by Nonpeptidic Mycobacterial Ligands

2. Structure of a human γδ T-cell antigen receptor

3. Human Vγ9Vδ2 T cells: promising new leads for immunotherapy of infections and tumors

4. Metabolic Routes as Targets for Immunological Discrimination of Host and Parasite

5. Chemical Synthesis and Biological Activity of Bromohydrin Pyrophosphate, a Potent Stimulator of Human γδ T Cells

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