Oxidative DNA Damage Following Microsome/Cu(II)-Mediated Activation of the Estrogens, 17β-Estradiol, Equilenin, and Equilin: Role of Reactive Oxygen Species
Author:
Affiliation:
1. James Graham Brown Cancer Center, and §Department of Pharmacology and Toxicology, University of Louisville, Louisville, Kentucky 40202, United States
Publisher
American Chemical Society (ACS)
Subject
Toxicology,General Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/tx200356v
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1. Ovary-intact, but not ovariectomized female ACI rats treated with 17beta-estradiol rapidly develop mammary carcinoma
2. Induction of high incidence of mammary tumour in female Noble rats with a combination of 17-oestradiol and testosterone
3. Catecholestrogens in the Induction of Tumors in the Kidney of the Syrian Hamster
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