Tubulin Binding, Protein-Bound Conformation in Solution, and Antimitotic Cellular Profiling of Noscapine and Its Derivatives-Reference-Cited by-同舟云学术

Tubulin Binding, Protein-Bound Conformation in Solution, and Antimitotic Cellular Profiling of Noscapine and Its Derivatives

Published:2012-02-27 Issue:5 Volume:55 Page:1920-1925
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Bennani Youssef L.¹,Gu Wenxin¹,Canales Angeles²,Dı́az Fernando J.³,Eustace Brenda K.¹,Hoover Russell R.¹,Jiménez-Barbero Jesus³,Nezami Azin¹,Wang Tiansheng¹

Affiliation:

1. Vertex Pharmaceuticals Inc., 130 Waverly Street, Cambridge Massachusetts 02139, United States

2. Departamento Química Orgánica I, Facultad Ciencias Químicas, Universidad Complutense de Madrid, Avenida Complutense s/n, 28040 Madrid, Spain

3. Department of Physical Chemistry, Centro de Investigaciones Biológicas, Consejo Superior de Investigaciones Cientı́ficas, Ramiro de Maeztu 9, 28040 Madrid

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm200848t

Reference15 articles.

1. Pierre-Jean Robiquet (Rennes, 14 janvier 1780-Paris, 29 avril 1840)

2. Pharmakokinetic properties of noscapine

3. SYNERGISTS AND ANTAGONISTS OF MITOTIC POISONS

4. Narcotin, ein Mitosegift

5. Opium alkaloid noscapine is an antitumor agent that arrests metaphase and induces apoptosis in dividing cells

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