Quinolone Carboxylic Acids as a Novel Monoketo Acid Class of Human Immunodeficiency Virus Type 1 Integrase Inhibitors

Author:

Sato Motohide1,Kawakami Hiroshi1,Motomura Takahisa1,Aramaki Hisateru1,Matsuda Takashi1,Yamashita Masaki1,Ito Yoshiharu1,Matsuzaki Yuji1,Yamataka Kazunobu1,Ikeda Satoru1,Shinkai Hisashi1

Affiliation:

1. Central Pharmaceutical Research Institute, JT Inc., 1-1 Murasaki-cho, Takatsuki, Osaka, 569-1125, Japan

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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1. Integrase;Metalloenzymes;2024

2. Synthetic approaches and application of clinically approved small-molecule Anti-HIV drugs: An update;European Journal of Medicinal Chemistry;2023-12

3. Base Promoted Synthesis of 4‐Quinolones Fused with Medium‐Sized Rings;European Journal of Organic Chemistry;2023-11-14

4. Chemoenzymatic Synthesis of Enantiopure Amino Alcohols from Simple Methyl Ketones;European Journal of Organic Chemistry;2023-08-04

5. The Integrase: An Overview of a Key Player Enzyme in the Antiviral Scenario;International Journal of Molecular Sciences;2023-07-29

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