Ternary Complexes of Gentamicin with Iron and Lipid Catalyze Formation of Reactive Oxygen Species
Author:
Affiliation:
1. Kresge Hearing Research Institute, Department of Otolaryngology, Department of Chemistry, and Department of Biological Chemistry, University of Michigan, Ann Arbor, Michigan 48109
Publisher
American Chemical Society (ACS)
Subject
Toxicology,General Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/tx0496946
Reference30 articles.
1. Aminoglycoside Antibiotics
2. Supplemental iron exacerbates aminoglycoside ototoxicity in vivo
3. Variable efficacy of radical scavengers and iron chelators to attenuate gentamicin ototoxicity in guinea pig in vivo
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