Synthesis and Characterization of a Novel Prostate Cancer-Targeted Phosphatidylinositol-3-kinase Inhibitor Prodrug-Reference-Cited by-同舟云学术

Synthesis and Characterization of a Novel Prostate Cancer-Targeted Phosphatidylinositol-3-kinase Inhibitor Prodrug

Published:2012-09-10 Issue:18 Volume:55 Page:8038-8046
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Baiz Daniele¹,Pinder Tanya A.²,Hassan Sazzad¹,Karpova Yelena¹,Salsbury Freddie³,Welker Mark E.²,Kulik George¹

Affiliation:

1. Department of Cancer Biology and Comprehensive Cancer Center, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, North Carolina 27157, United States

2. Department of Chemistry, Wake Forest University, Winston-Salem, North Carolina 27109, United States

3. Department of Physics, Wake Forest University, P.O. Box 7486, Winston-Salem, North Carolina 27109, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm300881a

Reference30 articles.

1. In VitroandIn VivoResponses of Advanced Prostate Tumors to PSMA ADC, an Auristatin-Conjugated Antibody to Prostate-Specific Membrane Antigen

2. Targeting the PI3K/AKT Pathway for the Treatment of Prostate Cancer

3. Mechanisms of prostate cancer cell survival after inhibition of AR expression

4. Targeted Therapy for Advanced Prostate Cancer: Inhibition of the PI3K/Akt/mTOR Pathway

5. Combination of PI3K/mTOR Inhibitors: Antitumor Activity and Molecular Correlates

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