1. Contribution from the School of Chemistry, University of St. Andrews, Purdie Building, St. Andrews KY16 9ST, U.K., Bute Medical School, University of St. Andrews, St. Andrews KY16 9TS, U.K., and Centre for Cardiovascular Science and MRC Centre for Inflammation Research, University of Edinburgh, Queen's Medical Research Institute, 47 Little France Crescent, Edinburgh EH16 4TJ, U.K.