Novel Selective PDE IV Inhibitors as Antiasthmatic Agents. Synthesis and Biological Activities of a Series of 1-Aryl-2,3-bis(hydroxymethyl)naphthalene Lignans-Reference-Cited by-同舟云学术

Novel Selective PDE IV Inhibitors as Antiasthmatic Agents. Synthesis and Biological Activities of a Series of 1-Aryl-2,3-bis(hydroxymethyl)naphthalene Lignans

Published:1996-01-01 Issue:14 Volume:39 Page:2696-2704
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Iwasaki Tameo¹,Kondo Kazuhiko¹,Kuroda Tooru¹,Moritani Yasunori¹,Yamagata Shinsuke¹,Sugiura Masaki¹,Kikkawa Hideo¹,Kaminuma Osamu¹,Ikezawa Katsuo¹

Affiliation:

1. Lead Optimization Research Laboratory, Tanabe Seiyaku Company, Ltd., 3-16-89, Kashima, Yodogawa, Osaka 532, Japan, and 2-2-50, Kawagishi, Toda, Saitama 335, Japan

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm9509096

Reference25 articles.

1. A New Generation of Phosphodiesterase Inhibitors: Multiple Molecular Forms of Phosphodiesterase and the Potential for Drug Selectivity

2. Primary sequence of cyclic nucleotide phosphodiesterase isozymes and the design of selective inhibitors

3. Prospects for selective cyclic nucleotide phosphodiesterase inhibitors in the treatment of bronchial asthma

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