Structural Simplification of Bioactive Natural Products with Multicomponent Synthesis. 3. Fused Uracil-Containing Heterocycles as Novel Topoisomerase-Targeting Agents-Reference-Cited by-同舟云学术

Structural Simplification of Bioactive Natural Products with Multicomponent Synthesis. 3. Fused Uracil-Containing Heterocycles as Novel Topoisomerase-Targeting Agents

Published:2011-03-09 Issue:7 Volume:54 Page:2012-2021
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Evdokimov Nikolai M.¹,Van slambrouck Severine¹,Heffeter Petra²,Tu Lee¹,Le Calvé Benjamin³,Lamoral-Theys Delphine³,Hooten Carla J.¹,Uglinskii Pavel Y.⁴,Rogelj Snezna⁵,Kiss Robert³,Steelant Wim F. A.¹,Berger Walter²,Yang Jeremy J.⁶,Bologa Cristian G.⁶,Kornienko Alexander¹,Magedov Igor V.¹

Affiliation:

1. Department of Chemistry, New Mexico Institute of Mining and Technology, Socorro, New Mexico 87801, United States

2. Institute of Cancer Research, Department of Medicine I, Medical University of Vienna, Borschkegasse 8a, 1090 Vienna, Austria

3. Laboratoire de Toxicologie and Laboratoire de Chimie Analytique, Toxicologie et Chimie Physique Appliquée, Institut de Pharmacie, Université Libre de Bruxelles, Brussels, Belgium

4. Department of Organic Chemistry, Timiryazev Agriculture Academy, Moscow 127550, Russia

5. Department of Biology, New Mexico Institute of Mining and Technology, Socorro, New Mexico 87801, United States

6. Division of Biocomputing, Department of Biochemistry and Molecular Biology, University of New Mexico School of Medicine, Albuquerque, New Mexico 87131, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm1009428

Reference31 articles.

1. Natural Products as Sources of New Drugs over the Period 1981−2002

2. Development of Natural Product-Derived Receptor Tyrosine Kinase Inhibitors Based on Conservation of Protein Domain Fold

3. Libraries from natural product-like scaffolds

4. “Multi-component Reactions : Emerging Chemistry in Drug Discovery” ‘From Xylocain to Crixivan’

5. Structural simplification of bioactive natural products with multicomponent synthesis: Dihydropyridopyrazole analogues of podophyllotoxin

Cited by 75 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Visible light–driven organic synthesis under iridium (IrIII)-complex photocatalysis;Visible Light-Driven Organic Synthesis;2025

2. Versatile anti-infective properties of pyrido- and dihydropyrido[2,3-d]pyrimidine-based compounds;Bioorganic & Medicinal Chemistry;2023-07

3. Recent advances on naphthoquinone-based photoinitiators of polymerization;European Polymer Journal;2023-07

4. Design and synthesis of uracil/thiouracil based quinoline scaffolds as topoisomerases I/II inhibitors for chemotherapy: A new hybrid navigator with DFT calculation;Bioorganic Chemistry;2023-07

5. Synthesis, DFT calculations, and anti-proliferative evaluation of pyrimidine and selenadiazolopyrimidine derivatives as dual Topoisomerase II and HSP90 inhibitors;Journal of Enzyme Inhibition and Medicinal Chemistry;2023-04-10