Michael Additions to (R)-1-Acetyl-5-isopropoxy-3-pyrrolin-2-one and Subsequent N-Acyliminium Ion Generation: Synthesis of Enantiopure 1-Azabicycles and Preparation of an Intermediate for a Projected Synthesis of Roseophilin
Author:
Affiliation:
1. Laboratory of Organic Chemistry, Amsterdam Institute of Molecular Studies, University of Amsterdam, Nieuwe Achtergracht 129, 1018 WS Amsterdam, The Netherlands
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/jo971854d
Reference20 articles.
1. (R)-1-Acetyl-5-isopropoxy-3-pyrrolin-2-one: a versatile chiral dienophile from (S)-malic acid
2. Lipase-Catalyzed Second-Order Asymmetric Transformations as Resolution and Synthesis Strategies for Chiral 5-(Acyloxy)-2(5H)-furanone and Pyrrolinone Synthons
3. (a) Koot, W.J.; Hiemstra, H.; Speckamp, W. N.Tetrahedron: Asymmetry1993,4, 1941.
4. Stereoselective synthesis of enantiopure 4,5-disubstituted pyrrolidin-2-ones by consecutive cuprate addition and N-acyliminium coupling
5. Stereochemistry of allylic alkylation of the tetracarbonyliron complexes of (R)-1-acetyl-5-isopropoxy-3-pyrrolin-2-one
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