1. Department of Environmental Science, Radboud University, Heyendaalseweg 135, 6525 AJ Nijmegen, The Netherlands, RIVM, Antonie van Leeuwenhoeklaan 9, 3721 MA Bilthoven, The Netherlands, and Molecular Ecology, Radboud University, Heyendaalseweg 135, 6525 AJ Nijmegen, The Netherlands