Unconventional Plasticity of HIV-1 Reverse Transcriptase: How Inhibitors Could Open a Connection “Gate” between Allosteric and Catalytic Sites-Reference-Cited by-同舟云学术

Unconventional Plasticity of HIV-1 Reverse Transcriptase: How Inhibitors Could Open a Connection “Gate” between Allosteric and Catalytic Sites

Published:2013-11-25 Issue:12 Volume:53 Page:3117-3122
ISSN:1549-9596
Container-title:Journal of Chemical Information and Modeling
language:en
Short-container-title:J. Chem. Inf. Model.

Author:

Bellucci Luca¹²,Angeli Lucilla¹,Tafi Andrea¹,Radi Marco¹³,Botta Maurizio¹⁴

Affiliation:

1. Dipartimento di Biotecnologie, Chimica e Farmacia, Università degli Studi di Siena, Via Aldo Moro 2, 53100 Siena, Italy

2. Centro S3, Istituto Nanoscienze Consiglio Nazionale delle Ricerche, CNR-NANO, via G. Campi 213/A, 41125 Modena, Italy

3. Dipartimento di Farmacia, Università degli Studi di Parma, Viale delle Scienze, 27/A, 43124 Parma, Italy

4. Sbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, College of Science and Technology, Temple University, BioLife Science Building, Suite 333, 1900 N. 12th Street, Philadelphia, Pennsylvania 19122, United States

Publisher

American Chemical Society (ACS)

Subject

Library and Information Sciences,Computer Science Applications,General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ci400414s

Reference36 articles.

1. Twenty-Six Years of Anti-HIV Drug Discovery: Where Do We Stand and Where Do We Go?

2. Strategies for the Design of HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors: Lessons from the Development of Seven Representative Paradigms

3. Chronic myeloid leukemia: 2012 update on diagnosis, monitoring, and management

4. Crystal Structure of HIV-1 Reverse Transcriptase Bound to a Non-Nucleoside Inhibitor with a Novel Mechanism of Action

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