Chloroquine Transport in Plasmodium falciparum. 1. Influx and Efflux Kinetics for Live Trophozoite Parasites Using a Novel Fluorescent Chloroquine Probe-Reference-Cited by-同舟云学术

Chloroquine Transport in Plasmodium falciparum. 1. Influx and Efflux Kinetics for Live Trophozoite Parasites Using a Novel Fluorescent Chloroquine Probe

Published:2009-09-16 Issue:40 Volume:48 Page:9471-9481
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Cabrera Mynthia¹,Natarajan Jayakumar¹,Paguio Michelle F.¹,Wolf Christian¹²,Urbach Jeffrey S.³,Roepe Paul D.¹⁴²

Affiliation:

1. Department of Chemistry

2. Center for Infectious Diseases

3. Department of Physics

4. Department of Biochemistry and Cellular and Molecular Biology

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/bi901034r

Reference38 articles.

1. Mutations in the P. falciparum Digestive Vacuole Transmembrane Protein PfCRT and Evidence for Their Role in Chloroquine Resistance

2. Evidence for a Substrate Specific and Inhibitable Drug Efflux System in Chloroquine Resistant Plasmodium falciparum Strains

3. Differences in trans-stimulated chloroquine efflux kinetics are linked to PfCRT in Plasmodium falciparum

4. The Antimalarial Drug Resistance Protein Plasmodium falciparum Chloroquine Resistance Transporter Binds Chloroquine

5. PfCRT and the trans-vacuolar proton electrochemical gradient: regulating the access of chloroquine to ferriprotoporphyrin IX

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2. Uptake of a fluorescently tagged chloroquine analogue is reduced in CQ-resistant compared to CQ-sensitive Plasmodium falciparum parasites;Malaria Journal;2019-10-07

3. Chemical Proteomics and Super-resolution Imaging Reveal That Chloroquine Interacts with Plasmodium falciparum Multidrug Resistance-Associated Protein and Lipids;ACS Chemical Biology;2018-09-12

4. Chloroquine exposure triggers distinct cellular responses in sensitive versus resistant Plasmodium falciparum parasites;Scientific Reports;2018-07-24

5. A Redox-Active Fluorescent pH Indicator for Detecting Plasmodium falciparum Strains with Reduced Responsiveness to Quinoline Antimalarial Drugs;ACS Infectious Diseases;2016-12-07