Structure−Activity Relationship Studies of Ethyl 2-Amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate (HA 14-1), an Antagonist for Antiapoptotic Bcl-2 Proteins To Overcome Drug Resistance in Cancer-Reference-Cited by-同舟云学术

Structure−Activity Relationship Studies of Ethyl 2-Amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate (HA 14-1), an Antagonist for Antiapoptotic Bcl-2 Proteins To Overcome Drug Resistance in Cancer

Published:2006-11-29 Issue:26 Volume:49 Page:7731-7739
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Doshi Jignesh M.¹,Tian Defeng¹,Xing Chengguo¹

Affiliation:

1. Department of Medicinal Chemistry, College of Pharmacy, University of Minnesota, 308 Harvard Street SE, Minneapolis, Minnesota 55455

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm060968r

Reference44 articles.

1. Pinedo, H. M.; Giaccone, G.Drug Resistance in the Treatment of Cancer; Cambridge University Press: Cambridge, U.K., 1998; pp 199−208.

2. Apoptosis: biochemical aspects and clinical implications

3. Angiogenesis and apoptosis

4. Genta. Proportion of Patients Who at the Time of Diagnosis Overexpress Bcl-2 Relative to a Normal Cellular Population.http://www.genta.com/genta/Products/bcl2.html(accessed 2006).

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