Novel Synthesis, Cytotoxic Evaluation, and Structure−Activity Relationship Studies of a Series of α-Alkylidene-γ-lactones and Lactams-Reference-Cited by-同舟云学术

Novel Synthesis, Cytotoxic Evaluation, and Structure−Activity Relationship Studies of a Series of α-Alkylidene-γ-lactones and Lactams

Published:2005-04-16 Issue:10 Volume:48 Page:3516-3521
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Janecki Tomasz¹,Błaszczyk Edyta¹,Studzian Kazimierz¹,Janecka Anna¹,Krajewska Urszula¹,Różalski Marek¹

Affiliation:

1. Institute of Organic Chemistry, Technical University of Łódź, Żeromskiego 116, 90-924 Łódź, Poland, Department of Medicinal Chemistry, Medical University of Łódź, Mazowiecka 6/8, 92-215, Poland, and Department of Pharmaucetical Biochemistry, Faculty of Pharmacy, Medical University of Łódź, Muszyńskiego 1, 90-151, Łódź, Poland

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm048970a

Reference30 articles.

1. Structural requirements of sesquiterpene lactones to inhibit LPS-induced nitric oxide synthesis in RAW 264.7 macrophages

2. The influence of glutathione and cysteine levels on the cytotoxicity of helenanolide type sesquiterpene lactones against KB cells

Cited by 119 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Domino Reactions Enable Zn-Mediated Direct Synthesis of Spiro-Fused 2-Oxindole-α-Methylene-γ-Butyrolactones/Lactams from Isatin Derivatives and 2-(Bromomethyl)acrylates;Molecules;2024-07-30

2. Visible-light-induced redox-neutral difunctionalization of alkenes and alkynes;Chemical Communications;2024

3. Insights into the anticancer activity of chiral alkylidene-β-lactams and alkylidene-γ-lactams: Synthesis and biological investigation;Bioorganic & Medicinal Chemistry;2022-06

4. Divergent Thio/Selenolactonization of Styrene-Type Carboxylic Acids and Amides: Synthesis of Chalcogenated Isobenzofuran-1 (3H)-ones and Isochroman-1-ones;Synlett;2022-04-18

5. A Rare Alder‐ene Cycloisomerization of 1,6‐Allenynes;Chemistry – A European Journal;2022-02