CCR2: Characterization of the Antagonist Binding Site from a Combined Receptor Modeling/Mutagenesis Approach-Reference-Cited by-同舟云学术

CCR2: Characterization of the Antagonist Binding Site from a Combined Receptor Modeling/Mutagenesis Approach

Published:2003-08-13 Issue:19 Volume:46 Page:4070-4086
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Berkhout Theo A.¹,Blaney Frank E.¹,Bridges Angela M.¹,Cooper David G.¹,Forbes Ian T.¹,Gribble Andrew D.¹,Groot Pieter H. E.¹,Hardy Adam¹,Ife Robert J.¹,Kaur Rejbinder¹,Moores Kitty E.¹,Shillito Helen¹,Willetts Jennifer¹,Witherington Jason¹

Affiliation:

1. Departments of Discovery Chemistry, Vascular Biology, and Gene Expression Sciences, GlaxoSmithKline, New Frontiers Science Park, Third Avenue, Harlow, Essex, UK CM19 5AD

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm030862l

Reference42 articles.

1. Opportunities for novel therapeutic agents acting at chemokine receptors

2. Cloning, in Vitro Expression, and Functional Characterization of a Novel Human CC Chemokine of the Monocyte Chemotactic Protein (MCP) Family (MCP-4) That Binds and Signals through the CC Chemokine Receptor 2B

3. Atherosclerosis — An Inflammatory Disease

4. Chemokines and atherosclerosis

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