Hydroxywarfarin Metabolites Potently Inhibit CYP2C9 Metabolism of S-Warfarin-Reference-Cited by-同舟云学术

Hydroxywarfarin Metabolites Potently Inhibit CYP2C9 Metabolism of S-Warfarin

Published:2010-04-29 Issue:5 Volume:23 Page:939-945
ISSN:0893-228X
Container-title:Chemical Research in Toxicology
language:en
Short-container-title:Chem. Res. Toxicol.

Author:

Jones Drew R.¹,Kim So-Young¹,Guderyon Michael¹,Yun Chul-Ho¹,Moran Jeffery H.¹,Miller Grover P.¹

Affiliation:

1. Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, School of Biological Sciences and Technology, Chonnam National University, Gwangju, South Korea, Public Health Laboratory, Arkansas Department of Health, Little Rock, Arkansas, and Pharmacology & Toxicology, University of Arkansas for Medical Sciences, Little Rock, Arkansas

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/tx1000283

Reference32 articles.

1. Why is Warfarin Underutilized in Patients with Atrial Fibrillation?

2. Oral Anticoagulants: Mechanism of Action, Clinical Effectiveness, and Optimal Therapeutic Range

3. Human P450 metabolism of warfarin

4. A comparison of the isomers of warfarin

5. Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: a role for P-4502C9 in the etiology of (S)-warfarin-drug interactions

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