A Mutual Prodrug Ester of GABA and Perphenazine Exhibits Antischizophrenic Efficacy with Diminished Extrapyramidal Effects-Reference-Cited by-同舟云学术

A Mutual Prodrug Ester of GABA and Perphenazine Exhibits Antischizophrenic Efficacy with Diminished Extrapyramidal Effects

Published:2008-03-26 Issue:9 Volume:51 Page:2858-2862
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Nudelman Abraham¹,Gil-Ad Irit¹,Shpaisman Nava¹,Terasenko Igor¹,Ron Hanna¹,Savitsky Kinneret¹,Geffen Yona¹,Weizman Abraham¹,Rephaeli Ada¹

Affiliation:

1. Department of Chemistry, Bar Ilan University, Ramat Gan, Israel, Laboratory of Biological Psychiatry and Laboratory of Pharmacology and Experimental Oncology, Felsenstein Medical Research Center, Sackler Faculty of Medicine, Tel-Aviv University, Ramat Aviv, Israel, and BioLineRx, Ltd., 19 Hartum Street, Jerusalem, Israel

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm7012453

Reference30 articles.

1. Serotonin and dopamine receptor gene polymorphisms and the risk of extrapyramidal side effects in perphenazine-treated schizophrenic patients

2. Cost-Effectiveness of Second-Generation Antipsychotics and Perphenazine in a Randomized Trial of Treatment for Chronic Schizophrenia

3. Dopamine: the rewarding years

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