Discovery of Small-Molecule Inhibitors of Bcl-2 through Structure-Based Computer Screening-Reference-Cited by-同舟云学术

Discovery of Small-Molecule Inhibitors of Bcl-2 through Structure-Based Computer Screening

Published:2001-11-01 Issue:25 Volume:44 Page:4313-4324
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Enyedy Istvan J.¹,Ling Yan¹,Nacro Kassoum¹,Tomita York¹,Wu Xihan¹,Cao Yeyu¹,Guo Ribo¹,Li Bihua¹,Zhu Xiaofeng¹,Huang Ying¹,Long Ya-Qiu¹,Roller Peter P.¹,Yang Dajun¹,Wang Shaomeng¹

Affiliation:

1. Structural Biology and Cancer Drug Discovery Program, Lombardi Cancer Center and Department of Oncology, Georgetown University Medical Center, 3970 Reservoir Road, Washington, D.C. 20007, and Laboratory of Medicinal Chemistry, National Cancer Institute, FCRDC, Building 376, Room 207, Fredrick, Maryland 21702

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm010016f

Reference43 articles.

1. BCL-2 family members and the mitochondria in apoptosis

2. The Bcl-2 Protein Family: Arbiters of Cell Survival

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4. Novel anticancer drug discovery

5. Apoptosis in Hormone-Responsive Malignancies

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