Synthesis and in Vitro and in Vivo Antimalarial Activity of N-(7-Chloro-4-quinolyl)-1,4-bis(3-aminopropyl)piperazine Derivatives-Reference-Cited by-同舟云学术

Synthesis and in Vitro and in Vivo Antimalarial Activity of N-(7-Chloro-4-quinolyl)-1,4-bis(3-aminopropyl)piperazine Derivatives

Published:2003-01-21 Issue:4 Volume:46 Page:542-557
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Ryckebusch Adina¹,Deprez-Poulain Rébecca¹,Maes Louis¹,Debreu-Fontaine Marie-Ange¹,Mouray Elisabeth¹,Grellier Philippe¹,Sergheraert Christian¹

Affiliation:

1. UMR 8525 CNRS, Université de Lille II, Institut de Biologie et Institut Pasteur de Lille, 1 rue du Professeur Calmette, B.P. 447, 59021 Lille Cedex, France, and Laboratoire de Biologie Parasitaire, IFR CNRS 63, Muséum National d'Histoire Naturelle, 61 rue Buffon, 75005 Paris, France, and Tibotec, B-32800 Mechelen, Belgium

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm020960r

Reference32 articles.

1. Factsheet No. 94; World Health Organization: Genever, Switzerland, 1998.

2. Antimalarial drug resistance: the pace quickens

3. Malarial haemozoin/β-haematin supports haem polymerization in the absence of protein

4. Inhibition of glutathione-dependent degradation of heme by chloroquine and amodiaquine as a possible basis for their antimalarial mode of action

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