Synthesis and Pharmacological Evaluation of Novel Nitrobenzenic Thromboxane Modulators as Antiplatelet Agents Acting on Both the Alpha and Beta Isoforms of the Human Thromboxane Receptor-Reference-Cited by-同舟云学术

Synthesis and Pharmacological Evaluation of Novel Nitrobenzenic Thromboxane Modulators as Antiplatelet Agents Acting on Both the Alpha and Beta Isoforms of the Human Thromboxane Receptor

Published:2006-05-24 Issue:12 Volume:49 Page:3701-3709
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Hanson Julien¹,Reynaud Denis¹,Qiao Na¹,Devel Philippe¹,Moray Anne-Lise¹,Renard Jean-François¹,Kelley Leanne P.¹,Winum Jean-Yves¹,Montero Jean-Louis¹,Kinsella B. Therese¹,Pirotte Bernard¹,Pace-Asciak Cecil R.¹,Dogné Jean-Michel¹

Affiliation:

1. Natural and Synthetic Drugs Research Centre, Department of Pharmacy, Laboratory of Medicinal Chemistry, University of Liège, 1, Av. de l'Hôpital, B-4000 Liège, Belgium, Program in Integrative Biology, Research Institute, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada M5G 1X8, School of Biomolecular & Biomedical Science, Conway Institute for Biomolecular and Biomedical Research, University College Dublin, Ireland, Department of Pharmacy, University of Namur, FUNDP, 61 rue...

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm060108a

Reference32 articles.

1. Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides.

2. New Developments on Thromboxane and Prostacyclin Modulators Part I: Thromboxane Modulators

3. Role of Prostacyclin in the Cardiovascular Response to Thromboxane A 2

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