Phenyl Amide Linker Improves the Pharmacokinetics and Pharmacodynamics of N-Terminally Mono-PEGylated Human Growth Hormone
Author:
Affiliation:
1. National Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China
2. University of Chinese Academy of Sciences, Beijing 100190, China
Funder
National Natural Science Foundation of China
Chinese Academy of Sciences
Natural Science Foundation of Beijing
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Pharmaceutical Science,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/mp500266c
Reference33 articles.
1. Effects of Growth Hormone on Glucose, Lipid, and Protein Metabolism in Human Subjects
2. Growth Hormone, Insulin-Like Growth Factors, and the Skeleton
3. Free insulin-like growth factors – measurements and relationships to growth hormone secretion and glucose homeostasis
4. Growth Hormone Regulation of Insulin-Like Growth Factor-I Gene Expression May Be Mediated by Multiple Distal Signal Transducer and Activator of Transcription 5 Binding Sites
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