Primary Drying Optimization in Pharmaceutical Freeze-Drying: A Multivial Stochastic Modeling Framework
Author:
Affiliation:
1. CAPE-Lab − Computer-Aided Process Engineering Laboratory, Department of Industrial Engineering, University of Padova, via Marzolo 9, 35131 Padova PD, Italy
2. GSK, via Fiorentina 1, 53100 Siena SI, Italy
Funder
Universit?? degli Studi di Padova
GlaxoSmithKline Biologicals SA
Publisher
American Chemical Society (ACS)
Subject
Industrial and Manufacturing Engineering,General Chemical Engineering,General Chemistry
Link
http://pubs.acs.org/doi/pdf/10.1021/acs.iecr.9b06402
Reference48 articles.
1. Aggressive conditions during primary drying as a contemporary approach to optimise freeze-drying cycles of biopharmaceuticals
2. Toward Optimal Operation Conditions of Freeze-Drying Processes via a Multilevel Approach
3. Determination of End Point of Primary Drying in Freeze-Drying Process Control
4. Freeze-drying of aqueous solutions: Maximum allowable operating temperature
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