Design of Multistage Counter-Current Liquid–Liquid Extraction for Small-Scale Applications

Author:

Weeranoppanant Nopphon1,Adamo Andrea1,Saparbaiuly Galym1,Rose Eleanor1,Fleury Christian2,Schenkel Berthold2,Jensen Klavs F.1ORCID

Affiliation:

1. Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States

2. Novartis Pharma AG, Postfach CH-4002, Basel, Switzerland

Funder

Novartis

Massachusetts Institute of Technology

Publisher

American Chemical Society (ACS)

Subject

Industrial and Manufacturing Engineering,General Chemical Engineering,General Chemistry

Reference46 articles.

1. Seader, J. D.; Henley, E. J.Separation Process Principles,2nd Edition;Wiley:Chichester, U.K., Hoboken, NJ, 2005; p xxxiv,756pp.

2. Continuous-flow synthesis and purification of atropine with sequential in-line separations of structurally similar impurities

3. Engineering chemistry: integrating batch and flow reactions on a single, automated reactor platform

4. Liquid-Liquid Extraction

5. Fuenfschilling, P.; Schenkel, B.Purification process for cyclosporin. U.S. Patent No. 6,620,325 B2, Sept. 16, 2003.

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