1. Centre for Process Systems Engineering, Department of Chemical Engineering, Imperial College London, London SW7 2AZ, U.K.
2. Process Systems Enterprise, Ltd., London W6 7HA, U.K.
3. Faculty of Chemical and Food Technology, Slovak University of Technology in Bratislava, 812 43 Bratislava, Slovakia
4. Small Molecule Design and Development, Lilly Research Laboratories, Eli Lilly & Company, Indianapolis, Indiana 46285, United States