Total Synthesis of Enantiopure Phalarine via a Stereospecific Pictet−Spengler Reaction: Traceless Transfer of Chirality from l-Tryptophan-Reference-Cited by-同舟云学术

Total Synthesis of Enantiopure Phalarine via a Stereospecific Pictet−Spengler Reaction: Traceless Transfer of Chirality from l-Tryptophan

Published:2010-05-28 Issue:24 Volume:132 Page:8506-8512
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Trzupek John D.¹,Lee Dongjoo¹,Crowley Brendan M.¹,Marathias Vasilios M.¹,Danishefsky Samuel J.¹

Affiliation:

1. Laboratory for Bioorganic Chemistry, Sloan-Kettering Institute for Cancer Research, 1275 York Avenue, New York, New York 10065, Pfizer Global Research and Development, 200 Cambridgepark Drive, Cambridge, Massachusetts 02140, and Department of Chemistry, Columbia University, Havemeyer Hall, 3000 Broadway, New York, New York 10027

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja1030968

Reference46 articles.

1. (−)-Phalarine, a furanobisindole alkaloid from Phalariscoerulescens

2. A route to functionalized mitosones

3. Approaches to the synthesis of the mitomycins. A route to the mitosanes involving activated cyclopropanes

4. Chemical Explorations Driven by an Enchantment With Mitomycinoids - A Twenty Year Account

5. Total Synthesis of 5-N-Acetylardeemin and Amauromine: Practical Routes to Potential MDR Reversal Agents

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