Design, Synthesis, and Biological Evaluation of Novel Carbohydrate-Based Sulfamates as Carbonic Anhydrase Inhibitors-Reference-Cited by-同舟云学术

Design, Synthesis, and Biological Evaluation of Novel Carbohydrate-Based Sulfamates as Carbonic Anhydrase Inhibitors

Published:2011-02-11 Issue:5 Volume:54 Page:1481-1489
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Lopez Marie¹,Trajkovic Jonathan¹,Bornaghi Laurent F.¹,Innocenti Alessio²,Vullo Daniela²,Supuran Claudiu T.²,Poulsen Sally-Ann¹

Affiliation:

1. Eskitis Institute for Cell and Molecular Therapies, Griffith University, Nathan, Queensland 4111, Australia

2. Polo Scientifico, Laboratorio di Chimica Bioinorganica, Rm. 188, Università degli Studi di Firenze, Via della Lastruccia 3, 50019 Sesto Fiorentino, Florence, Italy

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm101525j

Reference39 articles.

1. Carbonic anhydrases: novel therapeutic applications for inhibitors and activators

2. Carbonic Anhydrase as a Model for Biophysical and Physical-Organic Studies of Proteins and Protein−Ligand Binding

3. Hypoxia activates the capacity of tumor-associated carbonic anhydrase IX to acidify extracellular pH

4. Hypoxia-Inducible Carbonic Anhydrase IX and XII Promote Tumor Cell Growth by Counteracting Acidosis through the Regulation of the Intracellular pH

5. Regulation of tumor pH and the role of carbonic anhydrase 9

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