Potent Inhibition of Influenza Sialidase by a Benzoic Acid Containing a 2-Pyrrolidinone Substituent-Reference-Cited by-同舟云学术

Potent Inhibition of Influenza Sialidase by a Benzoic Acid Containing a 2-Pyrrolidinone Substituent

Published:1999-06-04 Issue:13 Volume:42 Page:2332-2343
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Atigadda Venkatram R.¹,Brouillette Wayne J.¹,Duarte Franco¹,Ali Shoukath M.¹,Babu Yarlagadda S.¹,Bantia Shanta¹,Chand Pooran¹,Chu Naiming¹,Montgomery John A.¹,Walsh David A.¹,Sudbeck Elise A.¹,Finley James¹,Luo Ming¹,Air Gillian M.¹,Laver Graeme W.¹

Affiliation:

1. Department of Chemistry and Center for Macromolecular Crystallography, University of Alabama at Birmingham, Birmingham, Alabama 35294, BioCryst Pharmaceuticals, Inc., 2190 Parkway Lake Drive, Birmingham, Alabama 35244, Department of Biochemistry and Molecular Biology, University of Oklahoma, Oklahoma City, Oklahoma 73190, and John Curtin School of Medical Research, Australian National University, Canberra 2601, Australia

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm980707k

Reference34 articles.

1. Site-directed mutagenesis of catalytic residues of influenza virus neuraminidase as an aid to drug design

2. Characterization of temperature sensitive influenza virus mutants defective in neuraminidase

3. Rational design of potent sialidase-based inhibitors of influenza virus replication

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