High-Resolution IMS–MS to Assign Additional Disulfide Bridge Pairing in Complementarity-Determining Regions of an IgG4 Monoclonal Antibody-Reference-Cited by-同舟云学术

High-Resolution IMS–MS to Assign Additional Disulfide Bridge Pairing in Complementarity-Determining Regions of an IgG4 Monoclonal Antibody

Published:2021-08-26 Issue:10 Volume:32 Page:2505-2512
ISSN:1044-0305
Container-title:Journal of the American Society for Mass Spectrometry
language:en
Short-container-title:J. Am. Soc. Mass Spectrom.

Author:

Deslignière Evolène¹²,Botzanowski Thomas¹²,Diemer Hélène¹²,Cooper-Shepherd Dale A.³,Wagner-Rousset Elsa⁴,Colas Olivier⁴,Béchade Guillaume³,Giles Kevin³^ORCID,Hernandez-Alba Oscar¹²,Beck Alain⁴^ORCID,Cianférani Sarah¹²^ORCID

Affiliation:

1. Laboratoire de Spectrométrie de Masse BioOrganique (LSMBO), IPHC, UMR 7178, Université de Strasbourg, CNRS, 67087 Strasbourg, France

2. Infrastructure Nationale de Protéomique ProFI − FR2048, 67087 Strasbourg, France

3. Waters Corporation, Stamford Avenue, Altrincham Road, Wilmslow, Cheshire SK9 4AX, U.K.

4. IRPF - Centre d’Immunologie Pierre-Fabre (CIPF), 74160 Saint-Julien-en-Genevois, France

Funder

Agence Nationale de la Recherche

Publisher

American Chemical Society (ACS)

Subject

Spectroscopy,Structural Biology

Link

https://pubs.acs.org/doi/pdf/10.1021/jasms.1c00151

Reference37 articles.

1. Antibodies to watch in 2021

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5. Human IgG2 Antibodies Display Disulfide-mediated Structural Isoforms

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