An Efficient Enantiopure Synthesis of a Pivotal Precursor to Substance P Antagonists1-Reference-Cited by-同舟云学术

An Efficient Enantiopure Synthesis of a Pivotal Precursor to Substance P Antagonists1

Published:2005-12-23 Issue:1 Volume:10 Page:142-148
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Nugent Thomas C.¹,Seemayer Robert¹

Affiliation:

1. Department of Chemistry, School of Engineering & Science, International University Bremen, Campus Ring 1, 28759 Bremen, Germany, and CV Therapeutics, Inc., Pharmaceutical Development and Manufacturing, 3172 Porter Drive, Palo Alto, California 94304, U.S.A.

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/op050213e

Reference21 articles.

1. Identification of a Series of 3-(Benzyloxy)-1-azabicyclo[2.2.2]octane Human NK1 Antagonists

2. The discovery of (2S,3S)-cis-2-(diphenylmethyl)-N-[(2-methoxyphenyl)methyl]-1-azabicyclo[2.2.2]octan-3-amine as a novel, nonpeptide substance P antagonist

3. Quinuclidine chemistry. 4. Diuretic properties of cis-3-amino-2-benzhydrylquinuclidine

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