Inverse 1,2,3-Triazole-1-yl-ethyl Substituted Hydroxamates as Highly Potent Matrix Metalloproteinase Inhibitors: (Radio)synthesis, in Vitro and First in Vivo Evaluation-Reference-Cited by-同舟云学术

Inverse 1,2,3-Triazole-1-yl-ethyl Substituted Hydroxamates as Highly Potent Matrix Metalloproteinase Inhibitors: (Radio)synthesis, in Vitro and First in Vivo Evaluation

Published:2013-08-16 Issue:17 Volume:56 Page:6858-6870
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Hugenberg Verena¹,Riemann Burkhard¹,Hermann Sven²,Schober Otmar¹,Schäfers Michael²³,Szardenings Katrin⁴,Lebedev Artem⁴,Gangadharmath Umesh⁴,Kolb Hartmuth⁴,Walsh Joseph⁴,Zhang Wei⁴,Kopka Klaus¹,Wagner Stefan¹

Affiliation:

1. Department of Nuclear Medicine, University Hospital Münster, Albert-Schweitzer-Campus 1, Building A1, D-48149 Münster, Germany

2. European Institute for Molecular Imaging, University of Münster, Mendelstrasse 11, D-48149 Münster, Germany

3. Interdisciplinary Centre of Clinical Research (IZKF), Albert-Schweitzer-Campus 1, Building D3, D-48149 Münster, Germany

4. Siemens Medical Solutions USA, Inc., 6100 Bristol Parkway, Culver City, California 90230, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm4006753

Reference47 articles.

1. Design and Therapeutic Application of Matrix Metalloproteinase Inhibitors

2. Matrix metalloproteinases: roles in cancer and metastasis

3. Matrix Metalloproteinases: Regulators of the Tumor Microenvironment

4. Roles of matrix metalloproteinases in cancer progression and their pharmacological targeting

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