1. Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, Department of Cancer Biology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, and Jim Ayers Institute for Precancer Detection and Diagnosis, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37232