Diastereoselective Alkylation of β-Amino Esters: Structural and Rate Studies Reveal Alkylations of Hexameric Lithium Enolates-Reference-Cited by-同舟云学术

Diastereoselective Alkylation of β-Amino Esters: Structural and Rate Studies Reveal Alkylations of Hexameric Lithium Enolates

Published:2004-11-23 Issue:50 Volume:126 Page:16559-16568
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

McNeil Anne J.¹,Toombes Gilman E. S.¹,Gruner Sol M.¹,Lobkovsky Emil¹,Collum David B.¹,Chandramouli Sithamalli V.¹,Vanasse Benoit J.¹,Ayers Timothy A.¹

Affiliation:

1. Contribution from the Department of Chemistry and Chemical Biology, Baker Laboratory, Cornell University, Ithaca, New York 14853-1301, Physics Department, Clark Hall, Cornell University, Ithaca, New York 14853-2501, and Process Development Chemistry, Aventis, Bridgewater, New Jersey 08807

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja045144i

Reference67 articles.

1. Optimization of the β-Aminoester class of factor Xa inhibitors. part 2: Identification of FXV673 as a potent and selective inhibitor with excellent In vivo anticoagulant activity

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