Geometrically and Conformationally Restrained Cinnamoyl Compounds as Inhibitors of HIV-1 Integrase: Synthesis, Biological Evaluation, and Molecular Modeling-Reference-Cited by-同舟云学术

Geometrically and Conformationally Restrained Cinnamoyl Compounds as Inhibitors of HIV-1 Integrase: Synthesis, Biological Evaluation, and Molecular Modeling

Published:1998-09-17 Issue:21 Volume:41 Page:3948-3960
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Artico Marino¹,Di Santo Roberto¹,Costi Roberta¹,Novellino Ettore¹,Greco Giovanni¹,Massa Silvio¹,Tramontano Enzo¹,Marongiu Maria E.¹,De Montis Antonella¹,La Colla Paolo¹

Affiliation:

1. Istituto Pasteur - Fondazione Cenci Bolognetti, Dipartimento di Studi Farmaceutici, Università di Roma “La Sapienza”, Piazzale A. Moro 5, I-00185 Roma, Italy, Dipartimento di Scienze Farmaceutiche, Università di Salerno, Piazza Vittorio Emanuele 9, I-84084 Penta (Salerno), Italy, Dipartimento di Chimica Farmaceutica e Tossicologica, Università di Napoli “Federico II”, Via D. Montesano 49, I-80131 Napoli, Italy, Dipartimento Farmaco Chimico Tecnologico, Università di Siena, Banchi di Sotto 55, I-53100...

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm9707232

Reference49 articles.

1. Crystal structures of HIV-1 protease-inhibitor complexes

2. Toward Improved Anti-HIV Chemotherapy: Therapeutic Strategies for Intervention with HIV Infections

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