Use of Virtual Screening, Flexible Docking, and Molecular Interaction Fields To Design Novel HMG-CoA Reductase Inhibitors for the Treatment of Hypercholesterolemia-Reference-Cited by-同舟云学术

Use of Virtual Screening, Flexible Docking, and Molecular Interaction Fields To Design Novel HMG-CoA Reductase Inhibitors for the Treatment of Hypercholesterolemia

Published:2007-11-29 Issue:10 Volume:112 Page:2007-2011
ISSN:1089-5639
Container-title:The Journal of Physical Chemistry A
language:en
Short-container-title:J. Phys. Chem. A

Author:

da Silva Vinicius B.¹,Taft Carlton A.¹,Silva Carlos H. T. P.¹

Affiliation:

1. Departamento de Ciências Farmacêuticas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Av. do Café, s/n, Monte Alegre, 14040-903, Ribeirão Preto-SP, Brasil, and Centro Brasileiro de Pesquisas Físicas, Rua Dr. Xavier Sigaud, 150, Urca, 22290-180, Rio de Janeiro-RJ, Brasil

Publisher

American Chemical Society (ACS)

Subject

Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jp075502e

Reference18 articles.

1. Current Methods in Medicinal Chemistry and Biological Physics; Taft, C. A., Silva, C. H. T. P., Eds.; Research Signpost: Kerala, India, 2007; Vol. 1.

2. Cancer and Aids: New Trends in Drug Design and Chemotherapy

3. Molecular dynamics, database screening, density functional and docking studies of novel RAR ligands in cancer chemotherapy

4. Structural Mechanism for Statin Inhibition of HMG-CoA Reductase

5. Crystal Structure of a Statin Bound to a Class II Hydroxymethylglutaryl-CoA Reductase

Cited by 20 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Onion Polyphenols as Multi-Target-Directed Ligands in MASLD: A Preliminary Molecular Docking Study;Nutrients;2024-04-20

2. Virtual Screening of HMG-CoA reductase inhibitors of West Bali National Park natural compounds database using machine learning;Proceedings of the 2022 International Conference on Computer, Control, Informatics and Its Applications;2022-11-22

3. Potential natural inhibitors of xanthine oxidase and HMG-CoA reductase in cholesterol regulation: in silico analysis;BMC Complementary Medicine and Therapies;2021-01-01

4. Quantum Chemistry Simulation of Biological Molecules;2020-11-30

5. In-Silico Analysis of Secondary Metabolites that Modulates Enzymes of Cholesterol Target;2020-07-25