Hypoxia and H2O2 Dual-Sensitive Vesicles for Enhanced Glucose-Responsive Insulin Delivery

Author:

Yu Jicheng12,Qian Chenggen13,Zhang Yuqi12,Cui Zheng4,Zhu Yong14,Shen Qundong3,Ligler Frances S.1,Buse John B.5,Gu Zhen125ORCID

Affiliation:

1. Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Raleigh, North Carolina 27695, United States

2. Center for Nanotechnology in Drug Delivery and Division of Molecular Pharmaceutics, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States

3. Department of Polymer Science & Engineering and Key Laboratory of High Performance Polymer Materials & Technology of MOE, School of Chemistry & Chemical Engineering, Nanjing University, Nanjing, 210023, China

4. Department of Mechanical and Aerospace Engineering, North Carolina State University, Raleigh, North Carolina 27695, United States

5. Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States

Funder

National Center for Advancing Translational Sciences

JDRF

North Carolina Translational and Clinical Sciences Institute

Publisher

American Chemical Society (ACS)

Subject

Mechanical Engineering,Condensed Matter Physics,General Materials Science,General Chemistry,Bioengineering

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