Ultra-stable Biomembrane Force Probe for Accurately Determining Slow Dissociation Kinetics of PD-1 Blockade Antibodies on Single Living Cells

Author:

An Chenyi1ORCID,Hu Wei1ORCID,Gao Jie1,Ju Bing-Feng1,Obeidy Peyman2,Zhao Yunduo Charles2,Tu Xiaoxuan3,Fang Weijia34,Ju Lining Arnold25,Chen Wei16ORCID

Affiliation:

1. Department of Cell Biology and Department of Cardiology of the Second Affiliated Hospital, Zhejiang University School of Medicine, State Key Laboratory of Fluid Power and Mechatronic Systems, Key Laboratory for Biomedical Engineering of Ministry of Education, and School of Mechanical Engineering, Zhejiang University, Hangzhou, China, 310058

2. School of Biomedical Engineering, Faculty of Engineering and Charles Perkins Centre, The University of Sydney, Camperdown, New South Wales Australia, 2006

3. Department of Medical Oncology, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China, 310000

4. Zhejiang Provincial Key Laboratory of Pancreatic Disease, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China, 310000

5. Heart Research Institute, Newtown, New South Wales Australia, 2042

6. State Key Laboratory for Modern Optical Instrumentation and Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Zhejiang University, Hangzhou, China, 310058

Funder

National Basic Research Program of China

Fundamental Research Funds for the Central Universities

Australian Research Council DECRA

Australian Research Council Discovery Project

NSW Cardiovascular Capacity Building Program (Early-Mid Career Research Grant)

University of Sydney Faculty of Engineering Major Equipment Scheme

National Science Foundation of China

National Heart Foundation Future Leader

Sydney Research Accelerator prize (SOAR)

Publisher

American Chemical Society (ACS)

Subject

Mechanical Engineering,Condensed Matter Physics,General Materials Science,General Chemistry,Bioengineering

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