Intelligent Pore Switch of Hollow Mesoporous Organosilica Nanoparticles for High Contrast Magnetic Resonance Imaging and Tumor-Specific Chemotherapy

Author:

Huang Lin1,Feng Jie1,Fan Wenpei2ORCID,Tang Wei3,Rong Xiaoxiang4,Liao Wangjun4,Wei Zhenni5,Xu Yikai1,Wu Aiguo5ORCID,Chen Xiaoyuan6,Shen Zheyu1ORCID

Affiliation:

1. Guangdong Provincial Key Laboratory of Construction and Detection in Tissue Engineering, Medical Imaging Center, Nanfang Hospital, School of Biomedical Engineering, Southern Medical University, 1023 Sha-Tai South Road, Guangzhou, Guangdong 510515, China

2. State Key Laboratory of Natural Medicines and Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases, Center of Advanced Pharmaceuticals and Biomaterials, China Pharmaceutical University, Nanjing, 210009, China

3. Departments of Pharmacy and Diagnostic Radiology, Faculty of Science and Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117559, Singapore

4. Department of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China

5. Cixi Institute of Biomedical Engineering, CAS Key Laboratory of Magnetic Materials and Devices, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, 1219 Zhong-guan West Road, Ning-bo, Zhe-jiang 315201, China

6. Departments of Diagnostic Radiology, Surgery, Chemical and Biomolecular Engineering, and Biomedical Engineering, Yong Loo Lin School of Medicine and Faculty of Engineering, National University of Singapore, Singapore 119074, Singapore

Funder

National Natural Science Foundation of China

Natural Science Foundation of Guangdong Province

Natural Science Foundation of Zhejiang Province

Guangzhou Key Research and Development Program of China

Publisher

American Chemical Society (ACS)

Subject

Mechanical Engineering,Condensed Matter Physics,General Materials Science,General Chemistry,Bioengineering

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