Scalable mRNA and siRNA Lipid Nanoparticle Production Using a Parallelized Microfluidic Device-Reference-Cited by-同舟云学术

Scalable mRNA and siRNA Lipid Nanoparticle Production Using a Parallelized Microfluidic Device

Published:2021-06-30 Issue:13 Volume:21 Page:5671-5680
ISSN:1530-6984
Container-title:Nano Letters
language:en
Short-container-title:Nano Lett.

Author:

Shepherd Sarah J.¹,Warzecha Claude C.²,Yadavali Sagar¹,El-Mayta Rakan¹,Alameh Mohamad-Gabriel³^ORCID,Wang Lili²,Weissman Drew³,Wilson James M.²,Issadore David¹⁴⁵,Mitchell Michael J.¹⁶⁷⁸⁹^ORCID

Affiliation:

1. Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States

2. Gene Therapy Program, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States

3. Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States

4. Department of Electrical and Systems Engineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States

5. Department of Chemical and Biomolecular Engineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States

6. Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States

7. Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States

8. Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States

9. Institute for Regenerative Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States

Funder

National Center for Advancing Translational Sciences

Publisher

American Chemical Society (ACS)

Subject

Mechanical Engineering,Condensed Matter Physics,General Materials Science,General Chemistry,Bioengineering

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.nanolett.1c01353

Reference62 articles.

1. RNA-Based Therapeutics: Current Progress and Future Prospects

2. The current state and future directions of RNAi-based therapeutics

3. Lipid nanoparticles for delivery of messenger RNA to the back of the eye

4. Non-viral vectors for gene-based therapy

5. Rational design of cationic lipids for siRNA delivery

Cited by 154 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Design and production of nanoparticles;Nanotechnology Tools for Infection Control;2025

2. Comprehensive analysis of lipid nanoparticle formulation and preparation for RNA delivery;International Journal of Pharmaceutics: X;2024-12

3. Advances in the design and delivery of RNA vaccines for infectious diseases;Advanced Drug Delivery Reviews;2024-10

4. Enhancing siRNA cancer therapy: Multifaceted strategies with lipid and polymer-based carrier systems;International Journal of Pharmaceutics;2024-09

5. Advances and prospects of RNA delivery nanoplatforms for cancer therapy;Acta Pharmaceutica Sinica B;2024-09