Liquid–Liquid Phase Separation Primes Spider Silk Proteins for Fiber Formation via a Conditional Sticker Domain-Reference-Cited by-同舟云学术

Liquid–Liquid Phase Separation Primes Spider Silk Proteins for Fiber Formation via a Conditional Sticker Domain

Published:2023-04-21 Issue:12 Volume:23 Page:5836-5841
ISSN:1530-6984
Container-title:Nano Letters
language:en
Short-container-title:Nano Lett.

Author:

Leppert Axel¹^ORCID,Chen Gefei²^ORCID,Lama Dilraj¹,Sahin Cagla¹³^ORCID,Railaite Vaida¹,Shilkova Olga²,Arndt Tina²^ORCID,Marklund Erik G.⁴^ORCID,Lane David P.¹,Rising Anna²⁵^ORCID,Landreh Michael¹⁶^ORCID

Affiliation:

1. Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, S-17165 Solna, Sweden

2. Department of Biosciences and Nutrition, Karolinska Institutet, S-14157 Huddinge, Sweden

3. Linderstro̷m-Lang Centre for Protein Science, Department of Biology, University of Copenhagen, 2200 Copenhagen, Denmark

4. Department of Chemistry − BMC, Uppsala University, S-75123 Uppsala, Sweden

5. Department of Anatomy Physiology and Biochemistry, Swedish University of Agricultural Sciences, 750 07 Uppsala, Sweden

6. Department of Cell and Molecular Biology, Uppsala University, S-75124 Uppsala, Sweden

Funder

Svenska Forskningsr?det Formas

Vetenskapsr?det

Novo Nordisk Fonden

Stiftelsen Olle Engkvist Byggm?stare

Cancerfonden

H2020 European Research Council

Publisher

American Chemical Society (ACS)

Subject

Mechanical Engineering,Condensed Matter Physics,General Materials Science,General Chemistry,Bioengineering

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.nanolett.3c00773

Reference24 articles.

1. Valence and patterning of aromatic residues determine the phase behavior of prion-like domains

2. Structural Studies of Amyloid Proteins at the Molecular Level

3. Generic nature of the condensed states of proteins

4. Spider silk self-assembly via modular liquid-liquid phase separation and nanofibrillation

5. An Engineered Spider Silk Protein Forms Microspheres

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