Nanoparticle-Catalyzed Transamination under Tumor Microenvironment Conditions: A Novel Tool to Disrupt the Pool of Amino Acids and GSSG in Cancer Cells

Author:

Bonet-Aleta Javier1234ORCID,Alegre-Requena Juan Vicente5,Martin-Martin Javier16,Encinas-Gimenez Miguel1234,Martín-Pardillos Ana124,Martin-Duque Pilar347,Hueso Jose L.1234ORCID,Santamaria Jesus1234ORCID

Affiliation:

1. Instituto de Nanociencia y Materiales de Aragon (INMA) CSIC-Universidad de Zaragoza, Campus Rio Ebro, Edificio I+D, C/Poeta Mariano Esquillor, s/n, 50018 Zaragoza, Spain

2. Department of Chemical and Environmental Engineering, University of Zaragoza, Campus Rio Ebro, C/María de Luna, 3, 50018 Zaragoza, Spain

3. Networking Res. Center in Biomaterials, Bioengineering and Nanomedicine (CIBER-BBN), Instituto de Salud Carlos III, 28029 Madrid, Spain

4. Instituto de Investigación Sanitaria (IIS) de Aragón, Avenida San Juan Bosco, 13, 50009 Zaragoza, Spain

5. Departamento de Química Inorgánica, Instituto de Síntesis Química y Catálisis Homogénea (ISQCH), CSIC-Universidad de Zaragoza, C/Pedro Cerbuna 12, 50009 Zaragoza, Spain

6. Department of Organic Chemistry, University of Zaragoza, 50009 Zaragoza Spain

7. Surgery Department, Medicine Medical School, University of Zaragoza, 50009 Zaragoza, Spain

Funder

European Research Council

Agencia Estatal de Investigaci?n

European Social Fund Plus

Publisher

American Chemical Society (ACS)

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