Structural Dynamics of Amyloid-β Protofibrils and Actions of Anti-Amyloid-β Antibodies as Observed by High-Speed Atomic Force Microscopy

Author:

Watanabe-Nakayama Takahiro1ORCID,Tsuji Mayumi2,Umeda Kenichi1,Oguchi Tatsunori23,Konno Hiroki1ORCID,Noguchi-Shinohara Moeko4,Kiuchi Yuji23,Kodera Noriyuki1,Teplow David B.5ORCID,Ono Kenjiro4ORCID

Affiliation:

1. WPI Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, Kakuma-machi, Kanazawa 920-1192, Japan

2. Pharmacological Research Center, Showa University, Tokyo 142-8555, Japan

3. Department of Pharmacology, Division of Medical Pharmacology, School of Medicine, Showa University, Shinagawa-ku, Tokyo 142-8555, Japan

4. Department of Neurology, Kanazawa University Graduate School of Medical Sciences, Kanazawa University, 13-1, Takara-machi, Kanazawa 920-8640, Japan

5. Department of Neurology, David Geffen School of Medicine at UCLA, University of California, 635 Charles E. Young Drive South, Los Angeles, California 90095-7334, United States

Funder

Ministry of Education, Culture, Sports, Science and Technology

Eisai

Japan Society for the Promotion of Science

Kanazawa University

Publisher

American Chemical Society (ACS)

Subject

Mechanical Engineering,Condensed Matter Physics,General Materials Science,General Chemistry,Bioengineering

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