Design of a Potent Combined Pseudopeptide Endothelin-A/Endothelin-B Receptor Antagonist, Ac-dBhg16-Leu-Asp-Ile-[NMe]Ile-Trp21 (PD 156252): Examination of Its Pharmacokinetic and Spectral Properties-Reference-Cited by-同舟云学术

Design of a Potent Combined Pseudopeptide Endothelin-A/Endothelin-B Receptor Antagonist, Ac-dBhg16-Leu-Asp-Ile-[NMe]Ile-Trp21 (PD 156252): Examination of Its Pharmacokinetic and Spectral Properties

Published:1997-07-01 Issue:14 Volume:40 Page:2228-2240
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Cody Wayne L.¹,He John X.¹,Reily Michael D.¹,Haleen Stephen J.¹,Walker Donnelle M.¹,Reyner Eric L.¹,Stewart Barbra H.¹,Doherty Annette M.¹

Affiliation:

1. Departments of Chemistry, Vascular and Cardiac Diseases, and Pharmacokinetics & Drug Metabolism, Parke-Davis Pharmaceutical Research, Division of Warner-Lambert Company, Ann Arbor, Michigan 48105

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm970161m

Reference72 articles.

1. Characterization of a coronary vasoconstrictor produced by cultured endothelial cells

2. A novel potent vasoconstrictor peptide produced by vascular endothelial cells

3. The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes.

4. A Novel Peptide, Vasoactive Intestinal Contractor, of a New (Endothelin) Peptide Family

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