Factors Influencing the Specificity of Inhibitor Binding to the Human and Malaria Parasite Dihydroorotate Dehydrogenases-Reference-Cited by-同舟云学术

Factors Influencing the Specificity of Inhibitor Binding to the Human and Malaria Parasite Dihydroorotate Dehydrogenases

Published:2012-06-15 Issue:12 Volume:55 Page:5841-5850
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Bedingfield Paul T. P.¹,Cowen Deborah¹,Acklam Paul¹,Cunningham Fraser¹,Parsons Mark R.¹,McConkey Glenn A.¹,Fishwick Colin W. G.¹,Johnson A. Peter¹

Affiliation:

1. Faculty of Biological Sciences, ‡School of Chemistry, and §Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, LS2 9JT, U.K.

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm300157n

Reference36 articles.

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2. Leflunomide: mode of action in the treatment of rheumatoid arthritis

3. Broad-spectrum antiviral that interferes with de novo pyrimidine biosynthesis

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