Function-Based Mutation-Resistant Synthetic Signaling Device Activated by HIV-1 Proteolysis
Author:
Affiliation:
1. Laboratory of Biotechnology, National Institute of Chemistry, Hajdrihova 19, 1000 Ljubljana, Slovenia
2. EN-FIST Centre of Excellence, Trg OF 13, 1000 Ljubljana, Slovenia
Funder
EN-FIST Center odlicnosti
Javna Agencija za Raziskovalno Dejavnost RS
Publisher
American Chemical Society (ACS)
Subject
Biochemistry, Genetics and Molecular Biology (miscellaneous),Biomedical Engineering,General Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/sb5002483
Reference31 articles.
1. Antiretroviral Treatment of Adult HIV Infection
2. Active human immunodeficiency virus protease is required for viral infectivity.
3. HIV-1 protease: mechanism and drug discovery
4. Engineering human immunodeficiency virus 1 protease heterodimers as macromolecular inhibitors of viral maturation.
5. Resistance of HIV Type 1 to Proteinase Inhibitor Ro 31-8959
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1. Designed protease-based signaling networks;Current Opinion in Chemical Biology;2022-06
2. Design of fast proteolysis-based signaling and logic circuits in mammalian cells;Nature Chemical Biology;2018-12-10
3. Locked and proteolysis-based transcription activator-like effector (TALE) regulation;Nucleic Acids Research;2016-01-08
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