Rational Design and Synthesis of an Orally Active Indolopyridone as a Novel Conformationally Constrained Cannabinoid Ligand Possessing Antiinflammatory Properties-Reference-Cited by-同舟云学术

Rational Design and Synthesis of an Orally Active Indolopyridone as a Novel Conformationally Constrained Cannabinoid Ligand Possessing Antiinflammatory Properties

Published:2003-04-26 Issue:11 Volume:46 Page:2110-2116
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Wrobleski Stephen T.¹,Chen Ping¹,Hynes, John¹,Lin Shuqun¹,Norris Derek J.¹,Pandit Chennagiri R.¹,Spergel Steven¹,Wu Hong¹,Tokarski John S.¹,Chen Xiaorong¹,Gillooly Kathleen M.¹,Kiener Peter A.¹,McIntyre Kim W.¹,Patil-koota Vina¹,Shuster David J.¹,Turk Lori A.¹,Yang Guchen¹,Leftheris Katerina¹

Affiliation:

1. Departments of Discovery Chemistry, Structural Biology and Modeling, and Immunology, Inflammation, and Pulmonary Discovery, Bristol-Myers Squibb, P.O. Box 4000, Princeton, New Jersey 08543-4000

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm020329q

Reference29 articles.

1. The endocannabinoid nervous system

2. Cannabinoids in Clinical Practice

3. Structure of a cannabinoid receptor and functional expression of the cloned cDNA

4. Molecular characterization of a peripheral receptor for cannabinoids

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