Total Synthesis of Spiruchostatin A via Chemoselective Macrocyclization using an Accessible Enantiomerically Pure Latent Thioester
Author:
Affiliation:
1. Department of Chemistry, Hobart and William Smith Colleges, Geneva, New York 14456
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/ol900436f
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1. Spiruchostatins A and B, novel gene expression-enhancing substances produced by Pseudomonas sp.
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3. Total Synthesis of the Depsipeptide FR-901375
4. Structure and Activity of Largazole, a Potent Antiproliferative Agent from the Floridian Marine Cyanobacterium Symploca sp.
5. Total Synthesis of Spiruchostatin A, a Potent Histone Deacetylase Inhibitor
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